Article

Developmental mitochondrial Complex I activity determines lifespan

2023-06-21

Abstract excerpt

Aberrant mitochondrial function has been associated with an increasingly large number of human disease states. Observations from in vivo models where mitochondrial function is altered suggest that adaptations to mitochondrial dysfunction may underpin disease pathology. We hypothesized that the severity of these maladaptations could be shaped by the plasticity of the system when mitochondrial dysfunction manifests...

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Literature Corpus work: a44a2e1c-3270-5b5a-a8d1-06b28715602a
DOI: 10.1101/2023.06.21.545894

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