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Mitochondria in the signaling pathways that control longevity and health span

12 Aug 2019

Abstract excerpt

Genetic and pharmacological intervention studies have identified evolutionarily conserved and functionally interconnected networks of cellular energy homeostasis, nutrient-sensing, and genome damage response signaling pathways, as prominent regulators of longevity and health span in various species. Mitochondria are the primary sites of ATP production and are key players in several other important cellular...

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PMID: 31415807
DOI: 10.1016/j.arr.2019.100940

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