Article

CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia

2017-09-29

Abstract excerpt

<h4>ABSTRACT</h4> Throughout metazoans, germ cells undergo incomplete cytokinesis to form syncytia connected by intercellular bridges. Formation of gametes ultimately requires bridge closure. Here, we investigate the contribution of the conserved bridge component centralspindlin to oocyte production in C. elegans . Centralspindlin is composed of the Rho family GTPase-activating protein (GAP) CYK-4/MgcRacGAP and...

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Literature Corpus work: 8be3cba0-525c-579d-9a44-51447fd25811
DOI: 10.1101/196279

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