Article

Single cell transcriptome atlas of immune cells in human small intestine and in celiac disease

2019-08-01

Abstract excerpt

Celiac disease (CeD) is an autoimmune disorder in which ingestion of dietary gluten triggers an immune reaction in the small intestine 1,2 . The CeD lesion is characterized by crypt hyperplasia, villous atrophy and chronic inflammation with accumulation of leukocytes both in the lamina propria (LP) and in the epithelium 3 , which eventually leads to destruction of the intestinal epithelium 1 and subsequent dige...

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Literature Corpus work: ec7ad3ae-253c-5d28-a013-09d5b8897281
DOI: 10.1101/721258

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