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A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables

2021-12-03

Abstract excerpt

The identification and understanding of gene-environment interactions can provide insights into the pathways and mechanisms underlying complex diseases. However, testing for gene-environment interaction remains a challenge since statistical power is often limited, the specification of environmental effects is nontrivial, and such misspecifications can lead to false positive findings. To address the lack of statist...

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Literature Corpus work
a3e5898e-5581-53d5-bc56-ebda7f7fad6a
DOI
10.1101/2021.12.01.469907
Open publication

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A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variablesDOI 10.1101/2021.12.01.469907
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