Back to search

Article

Identification of end stage renal disease associated loci in X chromosome: an X chromosome-wide association study

2024-10-28

Abstract excerpt

<title>Abstract</title> <p>Background X-chromosomal genetic variants have been understudied in end stage renal disease (ESRD), which hold the promise to provide valuable insights into sexually dimorphic traits and diseases. Methods We performed a X chromosome-wide association study (XWAS) in a Chinese cohort (N = 2750), comprising 1489 cases with ESRD and 1261 controls, to identify locus associated with ESRD ri...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a3d8f442-9fef-5454-b556-d607fb54abcd
DOI
10.21203/rs.3.rs-5294228/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of end stage renal disease associated loci in X chromosome: an X chromosome-wide association studyDOI 10.21203/rs.3.rs-5294228/v1
Identification of end-stage renal disease-associated loci in X chromosome: an X chromosome-wide association study.Semantic proximity
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.Semantic proximity
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Semantic proximity
Multi-Scalar Data Integration Decoding Risk Genes for Chronic Kidney DiseaseSemantic proximity
From GWAS to Translational Insights: Comprehensive Genetic Analysis of Nephrotic Syndrome from Multiple PopulationsSemantic proximity
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatmentsSemantic proximity
Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function.Semantic proximity
Genome-wide association analysis of cystatin c and creatinine kidney function in Chinese women.Semantic proximity
Sexual dimorphism in cancer: insights from transcriptional signatures in kidney tissue and renal cell carcinoma.Semantic proximity
Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney functionSemantic proximity
New mechanistic insights from alignment of accessible chromatin and renal lineage factor DNA-binding with genetics of kidney functionSemantic proximity
Chromatin State Maps of Blood Pressure-Relevant Renal Segments Reveal Potential Regulatory Role for SNPs.Semantic proximity
Select a neighboring publication to make it the new centre.