Article

Immunosuppressive myeloid cells induce mesenchymal-like breast cancer stem cells by a mechanism involving membrane-bound TGF-β1

2025-02-27

Abstract excerpt

<h4>Summary</h4> Suppressive myeloid cells play a central role in cancer escape from anti-tumor immunity. Beyond their immunosuppressive function, these cells are capable of exerting multiple other pro-tumoral activities, including the promotion of cancer cell survival, invasion and metastasis. The ability of some myeloid subsets to induce cancer stemness has recently emerged. Here we demonstrated that human immu...

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Literature Corpus work: 12a10c86-698c-5c68-a359-176151c8002c
DOI: 10.1101/2025.02.21.639264

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