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Article

The Interactions Between Cancer Stem Cells and the Innate Interferon Signaling Pathway

31 Mar 2020

Abstract excerpt

Interferons (IFNs) form a family of cytokines with pleiotropic effects that modulate the immune response against multiple challenges like viral infections, autoimmune diseases, and cancer. While numerous anti-tumor activities have been described for IFNs, IFNs have also been associated with tumor growth and progression. The effect of IFNs on apoptosis, angiogenesis, tumor cell immunogenicity, and modulation of...

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PMID: 32296435
DOI: 10.3389/fimmu.2020.00526

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