A single-cell map for the transcriptomic signatures of peripheral blood mononuclear cells in end-stage renal disease

Abstract excerpt

BACKGROUND: Immune aberrations in end-stage renal disease (ESRD) are characterized by systemic inflammation and immune deficiency. The mechanistic understanding of this phenomenon remains limited. METHODS: We generated 12 981 and 9578 single-cell transcriptomes of peripheral blood mononuclear cells (PBMCs) that were pooled from 10 healthy volunteers and 10 patients with ESRD by single-cell RNA sequencing....

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• Share to Chronic Kidney Disease and Diabetes
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