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WNT7B drives a program for pancreatic cancer subtype switching and progression

2024-12-20

Abstract excerpt

Hyperactivation of WNT signaling is a well-established hallmark of cancer. Various epithelial cancers express high levels of WNT7B and WNT10A that are not commonly expressed during tissue homeostasis, but rather associate with tissue development and regeneration. Although increased WNT7B/10A expression correlates with aggressive disease and lower patient survival rates, the mechanism by which these WNTs influence...

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Literature Corpus work
a3808c2b-7886-53cb-aeff-894ea0b43525
DOI
10.1101/2024.12.18.628910
Open publication

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WNT7B drives a program for pancreatic cancer subtype switching and progressionDOI 10.1101/2024.12.18.628910
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