Article

Single-Cell Cross-Species Profiling identifies Conserved Transcriptional Networks in Early Pancreatic Tumourigenesis

2026-03-05

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer and carries the poorest prognosis among all cancers, largely because it is frequently diagnosed at metastatic stages. It is therefore critical to identify reliable markers of preinvasive stages and to decipher the network driving preinvasive lesions to invasive carcinoma. Here, we generated a zebrafish model in which KRAS G12D is...

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Literature Corpus work: 7dd92c32-94af-5a91-bab8-af5c15a219c0
DOI: 10.64898/2026.03.03.708839

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