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The Global Landscape of Genetic Variation in Parkinson’s disease: Multi-Ancestry Insights into Established Disease Genes and their Translational Relevance

2025-07-11

Abstract excerpt

<h4>Background:</h4> The genetic architecture of Parkinson’s disease (PD) varies considerably across ancestries, yet most genetic studies have focused on individuals of European descent, limiting insights into the genetic landscape of PD at a global scale. <h4>Methods:</h4> We conducted a large-scale, multi-ancestry investigation of causal and risk variants in PD-related genes. Using genetic datasets from the Gl...

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Literature Corpus work
09e772f8-2a3d-5bdd-81ce-5e9fbc4849f3
DOI
10.1101/2025.07.08.25330815
Open publication

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The Global Landscape of Genetic Variation in Parkinson’s disease: Multi-Ancestry Insights into Established Disease Genes and their Translational RelevanceDOI 10.1101/2025.07.08.25330815
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