Article

Combination of single cell sequencing data and GWAS summary statistics reveals genetically-influenced liver cell types for primary biliary cholangitis

2021-08-24

Abstract excerpt

<h4>Importance</h4> Primary biliary cholangitis (PBC) is a classical autoimmune disease, which is highly influenced by genetic determinants. Many genome-wide association studies (GWAS) have reported that numerous genetic loci were significantly associated with PBC susceptibility. However, the effects of genetic determinants on liver cells and its immune microenvironment for PBC remain unclear. <h4>Objective</h4> T...

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Literature Corpus work: 4b6d22ea-bf46-5b54-a665-5fa475c80fab
DOI: 10.1101/2021.08.18.21262250

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