Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell RNA sequencing reveals the pro-inflammatory roles of liver-resident Th1-like cells in primary biliary cholangitis

7 Oct 2024

Abstract excerpt

Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by multilineage immune dysregulation, which subsequently causes inflammation, fibrosis, and even cirrhosis of liver. Due to the limitation of traditional assays, the local hepatic immunopathogenesis of PBC has not been fully characterized. Here, we utilize single-cell RNA sequencing technology to depict the immune cell landscape...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Disease Diagnosis and Treatment
Share to Liver Diseases and Immunity
Share to Pediatric Hepatobiliary Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39375367
DOI: 10.1038/s41467-024-53104-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell RNA sequencing reveals the pro-inflammatory roles of liver-resident Th1-like cells in primary biliary cholangitisPMID 39375367Read ↗

Single-cell mass cytometry on peripheral blood identifies immune cell subsets associated with primary biliary cholangitisSemantic proximity Read ↗

Single-cell and spatial transcriptomics reveals the human liver immunological landscape and myeloid dysfunction in PSCSemantic proximity Read ↗

Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liverSemantic proximity Read ↗

Single‐cell RNA sequencing reveals the heterogeneity and intercellular communication of hepatic stellate cells and macrophages during liver fibrosisSemantic proximity Read ↗

Single-Cell Transcriptomic Landscape of Intrahepatic B Cells in NASHSemantic proximity Read ↗

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cellsSemantic proximity Read ↗

Uncovering the Single-cell Transcriptomic Signatures and Pathogenesis of Mucosal-associated Invariant T cells during Nonalcoholic SteatohepatitisSemantic proximity Read ↗

Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progressionSemantic proximity Read ↗

Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosisSemantic proximity Read ↗

CD4 <sup>+</sup> T cells promote fibrosis during metabolic dysfunction-associated steatohepatitisSemantic proximity Read ↗

Immunogenomics of cholangiocarcinomaSemantic proximity Read ↗

IL-17 Signaling in Primary Sclerosing Cholangitis Patient-Derived OrganoidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.