Article

Identification of MAZ as a novel transcription factor regulating erythropoiesis

2020-05-10

Abstract excerpt

<h4>ABSTRACT</h4> Erythropoiesis requires a combination of ubiquitous and tissue-specific transcription factors. Here, through DNA affinity purification followed by mass spectrometry, we have identified the widely expressed protein MAZ (Myc-associated zinc finger) as a transcription factor that binds to the promoter of the erythroid-specific human α-globin gene. Genome-wide mapping in primary human erythroid cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a30f1d4a-11c2-5a0f-abae-c6de6ba86353
DOI: 10.1101/2020.05.10.087254

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of MAZ as a novel transcription factor regulating erythropoiesisDOI 10.1101/2020.05.10.087254Read

Regulation of GATA1 levels in erythropoiesisSemantic proximity Read

Genomic Organization and Expression of a Human Gene for Myc-associated Zinc Finger Protein (MAZ)Semantic proximity Read

N <sup>6</sup> -methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesisSemantic proximity Read

Erythropoiesis: insights from a genomic perspectiveSemantic proximity Read

The H3K4 methyltransferase KMT2D is an essential cofactor for GATA1 at erythroid gene enhancersSemantic proximity Read

An overexpression platform reveals the functional diversity of human KRAB-Zinc Finger Proteins in maintaining cellular homeostasisSemantic proximity Read

SIX1 Reprograms Myogenic Transcription Factors to Maintain the Rhabdomyosarcoma undifferentiated stateSemantic proximity Read

Epigenetic and Transcriptional Control of ErythropoiesisSemantic proximity Read

High Resolution Methylome Analysis Reveals Widespread Functional Hypomethylation during Adult Human ErythropoiesisSemantic proximity Read

Dissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells using gene editing, RNAseq and proteomicsSemantic proximity Read

A Unique Epigenomic Landscape Defines Human ErythropoiesisSemantic proximity Read

ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expressionSemantic proximity Read