Article

"Transcriptional Regulation of human NMNAT2: Insights from 3D Genome Sequencing and Bioinformatics"

2024-11-08

Abstract excerpt

<h4> Abstract </h4> Nicotinamide mononucleotide adenylyl transferases 2 (NMNAT2) is a crucial nicotinamide adenine dinucleotide (NAD)-synthesizing enzyme essential for neuronal health. In the Religious Orders Study/Memory and Aging Project (ROSMAP), human brain levels of NMNAT2 mRNA positively correlated with cognitive capabilities in older adults. NMNAT2 mRNA abundance is significantly reduced following various...

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Literature Corpus work: a30570ad-bbe2-54b8-aaf6-9e3682e6b67b
DOI: 10.1101/2024.11.07.622375

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