Article

NETSseq Reveals Inflammatory and Aging Mechanisms in Distinct Cell Types Driving Cerebellar Decline in Ataxia Telangiectasia

2025-05-16

Abstract excerpt

<h4>Summary</h4> The cellular and molecular changes driving the neurological abnormalities associated with ataxia – telangiectasia (A-T) are not well understood. Here, we applied our proprietary Nuclear Enriched Transcript Sort sequencing (NETSseq) platform to investigate changes in cell type composition and gene expression in human cerebellar post-mortem tissue from A-T and control donors. Compared to single-nuc...

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Literature Corpus work: 51ede9c8-d934-50b5-a792-df4099fa5226
DOI: 10.1101/2025.05.13.653662

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NETSseq Reveals Inflammatory and Aging Mechanisms in Distinct Cell Types Driving Cerebellar Decline in Ataxia TelangiectasiaDOI 10.1101/2025.05.13.653662Read

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