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NeuID, a novel neuron-specific lncRNA, resolves a key epigenetic mechanism linking gene silencing to Alzheimer’s disease

2025-06-03

Abstract excerpt

The increasing evidence that non-coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein-coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized. Here, we identify a previously unstudied lncRNA, which we named Neu ronal Id entity ( NeuID )—a conserved, brain-enriched...

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Literature Corpus work
0f1f0c02-1c16-5a8a-8ac3-2a249c075e06
DOI
10.1101/2025.06.01.657217
Open publication

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NeuID, a novel neuron-specific lncRNA, resolves a key epigenetic mechanism linking gene silencing to Alzheimer’s diseaseDOI 10.1101/2025.06.01.657217
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