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A polyomavirus-positive Merkel cell carcinoma mouse model supports a unified cancer origin

2025-05-09

Abstract excerpt

The Germ Cell Theory, rooted in developmental biology, has significantly advanced both the understanding and curative treatment of rare germ cell cancers (GCCs). In contrast, somatic cancer research - long dominated by the Somatic Mutation Theory - has stagnated due to fragmented, mutation-centric approaches that lack a unifying conceptual framework and have yielded only limited clinical progress. GCC research ide...

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Literature Corpus work
a2ee4842-382f-5a17-becc-aba166c46d08
DOI
10.1101/2025.05.06.652325
Open publication

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A polyomavirus-positive Merkel cell carcinoma mouse model supports a unified cancer originDOI 10.1101/2025.05.06.652325
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