Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma

4 Jan 2017

Abstract excerpt

Merkel cell polyomavirus is the primary etiological agent of the aggressive skin cancer Merkel cell carcinoma (MCC). Recent studies have revealed that UV radiation is the primary mechanism for somatic mutagenesis in nonviral forms of MCC. Here, we analyze the whole transcriptomes and genomes of primary MCC tumors. Our study reveals that virus-associated tumors have minimally altered genomes compared to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Multiple Sclerosis Research Studies
Share to Polyomavirus and related diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28049147
DOI: 10.1128/mbio.02079-16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell CarcinomaPMID 28049147Read ↗

Mutational Landscape of Virus- and UV-Associated Merkel Cell Carcinoma Cell Lines Is Comparable to Tumor TissueSemantic proximity Read ↗

UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas.Semantic proximity Read ↗

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma.Semantic proximity Read ↗

The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma.Semantic proximity Read ↗

From Merkel Cell Polyomavirus Infection to Merkel Cell Carcinoma OncogenesisSemantic proximity Read ↗

Molecular Mechanisms of Merkel Cell Polyomavirus Transformation and ReplicationSemantic proximity Read ↗

Merkel Cell Polyomavirus‒Negative Merkel Cell Carcinoma Originating from In Situ Squamous Cell Carcinoma: A Keratinocytic Tumor with Neuroendocrine DifferentiationSemantic proximity Read ↗

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinomaSemantic proximity Read ↗

Clonal Integration of a Polyomavirus in Human Merkel Cell CarcinomaSemantic proximity Read ↗

Update on Merkel Cell Carcinoma.Semantic proximity Read ↗

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy.Semantic proximity Read ↗

Molecular Pathogenesis of Merkel Cell Carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.