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Merkel Cell Polyomavirus (MCPyV) and Cancers: Emergency Bell or False Alarm?

11 Nov 2022

Abstract excerpt

Merkel cell polyomavirus (MCPyV), the sole member of Polyomavirus associated with oncogenesis in humans, is the major causative factor of Merkel cell carcinoma (MCC), a rare, neuroendocrine neoplasia of the skin. Many aspects of MCPyV biology and oncogenic mechanisms remain poorly understood. However, it has been established that oncogenic transformation is the outcome of the integration of the viral genome into...

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PMID: 36428641
DOI: 10.3390/cancers14225548

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