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Article

Hedgehog Signaling in Gastrointestinal Development and Disease

1 Feb 2002

Abstract excerpt

The development of the gastrointestinal (GI) tract and its associated parenchymal organs depends on Hedgehog signals from the endoderm to the surrounding mesoderm. During development, Hedgehog signaling is essential for patterning the GI tract along anterior-posterior (A-P), dorsal-ventral (D-V), and radial axes, as well as in maintenance of stem cells. Our knowledge about these roles for Hedgehog signaling is...

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PMID: 11898849
DOI: 10.2174/1566524023363130

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