Article

Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma

2023-08-03

Abstract excerpt

<title>Abstract</title> <p>Hedgehog (Hh) signaling is essential for development, homeostasis, and regeneration<sup>1</sup>. Misactivation of the Hh pathway underlies medulloblastoma, the most common malignant brain tumor in children, and basal cell carcinoma (BCC), the most common cancer in the United States<sup>2</sup>. Primary cilia regulate Hh signal transduction<sup>3</sup>, but target genes that drive cell f...

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Literature Corpus work: 31192234-e14e-5a56-8a64-e3dc5fc9e6c2
DOI: 10.21203/rs.3.rs-3058335/v1

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