Article

Improved integration of single cell transcriptome data demonstrated on heart failure in mice and men

2023-03-15

Abstract excerpt

Biomedical research frequently uses murine models to study disease mechanisms. However, the translation of these findings to human disease remains a significant challenge. In order to improve the comparability of mouse and human data, we present a cross-species integration pipeline for single-cell transcriptomic assays. The pipeline merges expression matrices and assigns clear orthologous relationships. Starting f...

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Literature Corpus work: a2b6cd0f-1aee-5beb-9dfd-051a624a9c34
DOI: 10.1101/2023.03.15.532742

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