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Article

A Cross-Tissue Transcriptome Association Study Revealed Novel Susceptibility Genes for Chronic Obstructive Pulmonary Disease.

International journal of chronic obstructive pulmonary disease - 1 Jan 2026

Luan Hao, Wang Tianhua, Su Xinjie, Zhao Junde, Yuan Zi, Ding Shengkai, Yang Yikun

Abstract excerpt

Background: Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation, with its pathogenesis remaining elusive. Genetic factors are recognized as crucial factors in the pathogenesis of COPD. Methods: This study employed transcriptome-wide association studies (TWAS) and single cell transcriptome analysis to identify predisposition genes and potential mechanisms for COPD....

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Source

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Identifiers

PMID: 41821648
DOI: 10.2147/COPD.S578900
PMCID: PMC12978012

Genes

DNAJA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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