Article

Pedigree Investigation, Clinical Characteristics and Prognosis Analysis of Hematological Disease Patients with Germline TET2 Mutation

2021-04-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>More and more germline gene mutations have been discovered in hematological malignances with the development of next gene sequencing (NGS). Tet methylcytosine dioxygenase 2 (TET2) is one of the most common mutation genes in hematological neoplasms. We aimed to analyzed whether germline TET2 mutation has a family aggregation or is a tumor predisposition gene. Fur...

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Literature Corpus work: a2b198cf-e9e2-5556-ac10-aeee12b16344
DOI: 10.21203/rs.3.rs-378431/v1

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