Article
Pedigree investigation, clinical characteristics, and prognosis analysis of haematological disease patients with germline TET2 mutation.
BMC cancer - 12 Mar 2022
Wu Xia, Deng Jili, Zhang Nanchen, Liu Xiaoyan, Zheng Xue, Yan Tianyou, Ye Wu, Gong Yuping
Abstract excerpt
BACKGROUND: Increasing germline gene mutations have been discovered in haematological malignancies with the development of next-generation sequencing (NGS), which is critical for proper clinical management and long-term follow-up of affected individuals. Tet methylcytosine dioxygenase 2 (TET2) is one of the most common mutations in haematological neoplasms. We aimed to compare the clinical characteristics of...
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