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Article

Clinical characterization of the mutational landscape of 24,639 real-world samples from patients with myeloid malignancies.

Cancer genetics - 1 Nov 2023

Hogg Grant, Severson Eric A, Cai Li, Hoffmann Heidi M, Holden Kimberly A, Fitzgerald Kerry, Kenyon Angela, Zeng Qiandong, Mooney Michael, Gardner Sabrina, Chen Wenjie, Nagan Narasimhan, Boles Deborah, Parker Scott, Richman Tamara J, Letovsky Stanley, Dong Henry, Anderson Steven M, Ramkissoon Shakti, Reddy Prasanth, Eisenberg Marcia, Chenn Anjen, Jensen Taylor J

Abstract excerpt

Myeloid neoplasms represent a broad spectrum of hematological disorders for which somatic mutation status in key driver genes is important for diagnosis, prognosis and treatment. Here we summarize the findings of a targeted, next generation sequencing laboratory developed test in 24,639 clinical myeloid samples. Data were analyzed comprehensively and as part of individual cohorts specific to acute myeloid...

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PMID: 37586297
DOI: 10.1016/j.cancergen.2023.07.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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