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Article

The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation.

Genes & development - 1 Apr 2010

Liu Hai-Kun, Wang Ying, Belz Thorsten, Bock Dagmar, Takacs Andrea, Radlwimmer Bernhard, Barbus Sebastian, Reifenberger Guido, Lichter Peter, Schütz Günther

Abstract excerpt

Malignant gliomas are the most common primary brain tumors, and are associated with frequent resistance to therapy as well as poor prognosis. Here we demonstrate that the nuclear receptor tailless (Tlx), which in the adult is expressed exclusively in astrocyte-like B cells of the subventricular z...

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Identifiers

PMID: 20360385
DOI: 10.1101/gad.560310
PMCID: PMC2849125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20360385-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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