Article

<i>Platr4</i> is an ESC-specific lncRNA that exhibits its function downstream on meso/endoderm lineage commitment

2021-12-21

Abstract excerpt

<h4>Summary</h4> The mammalian genome encodes thousands of long non-coding RNAs (lncRNAs) that are developmentally regulated and differentially expressed across tissues, suggesting possible roles in cellular differentiation. Despite this expression pattern, little is known about how lncRNAs influence lineage commitment at the molecular level. Here, we reveal that perturbation of an embryonic stem cell (ESC)-speci...

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Literature Corpus work: a2806931-ea2e-5681-bd98-43aa6c44a807
DOI: 10.1101/2021.12.20.473435

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