Article

Organ-specific and conserved regulatory logic orchestrates gene expression in the embryonic mesothelium

2025-08-06

Abstract excerpt

<h4>Summary</h4> The embryonic coelomic mesothelium undergoes epithelial-to-mesenchymal transition (EMT) to promote vascular growth and parenchymal development. A prominent example is the epicardium, which plays an essential role during heart development. Little is known about the mechanisms behind gene regulation in the coelomic mesothelium, or the organ-specific enhancer logic that endows specialization. Using...

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Literature Corpus work: 26225424-dda3-5789-b6ef-7624a470a3b8
DOI: 10.1101/2025.08.06.668886

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