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The lncRNA DEANR1 Facilitates Human Endoderm Differentiation by Activating FOXA2 Expression

1 Apr 2015

Abstract excerpt

Long non-coding RNAs (lncRNAs) regulate diverse biological processes, including cell lineage specification. Here, we report transcriptome profiling of human endoderm and pancreatic cell lineages using purified cell populations. Analysis of the data sets allows us to identify hundreds of lncRNAs that exhibit differentiation-stage-specific expression patterns. As a first step in characterizing these lncRNAs, we...

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PMID: 25843708
DOI: 10.1016/j.celrep.2015.03.008

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