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Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis

2023-09-07

Abstract excerpt

Clonal hematopoiesis (CH), characterized by blood cells predominantly originating from a single mutated hematopoietic stem cell, is linked to diverse aging-related diseases, including hematologic malignancy and atherosclerotic cardiovascular disease (ASCVD). While CH is common among older adults, the underlying factors driving its development are largely unknown. To address this, we performed whole-exome sequencin...

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Literature Corpus work
3b28007e-91c7-5ac4-9930-bea33ce0715f
DOI
10.1101/2023.09.05.23295093
Open publication

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Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesisDOI 10.1101/2023.09.05.23295093
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