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Article

Haematopoietic ageing through the lens of single-cell technologies.

Disease models & mechanisms - 22 Jan 2021

Strzelecka Paulina M, Damm Frederik

Abstract excerpt

Human lifespan is now longer than ever and, as a result, modern society is getting older. Despite that, the detailed mechanisms behind the ageing process and its impact on various tissues and organs remain obscure. In general, changes in DNA, RNA and protein structure throughout life impair their function. Haematopoietic ageing refers to the age-related changes affecting a haematopoietic system. Aged blood cells...

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Identifiers

PMID: 33735102
DOI: 10.1242/dmm.047340
PMCID: PMC7847262

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