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Article

Relationships between the circadian system and Alzheimer's disease-like symptoms in Drosophila.

PloS one - 1 Jan 2014

Long Dani M, Blake Matthew R, Dutta Sudeshna, Holbrook Scott D, Kotwica-Rolinska Joanna, Kretzschmar Doris, Giebultowicz Jadwiga M

Abstract excerpt

Circadian clocks coordinate physiological, neurological, and behavioral functions into circa 24 hour rhythms, and the molecular mechanisms underlying circadian clock oscillations are conserved from Drosophila to humans. Clock oscillations and clock-controlled rhythms are known to dampen during aging; additionally, genetic or environmental clock disruption leads to accelerated aging and increased susceptibility to...

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Identifiers

PMID: 25171136
DOI: 10.1371/journal.pone.0106068
PMCID: PMC4149435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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