Article
Circadian rhythm in neurodegenerative disease: the role of RNA modifications and potential application of RNA-based therapeutics
2024-09-21
Abstract excerpt
Neurodegenerative diseases usually present as progressive impairment of the motor or mental functions of the central or peripheral nervous system, which is often linked to genetic and biochemical factors. The main features include synaptic and neuronal deficits, abnormal protein homeostasis, DNA and RNA defects, inflammation, and pathological protein aggregation. Clinical evidence suggests that circadian rhythms a...
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Identifiers and source
- Literature Corpus work
- 1148cdd6-142e-592e-92bf-03b7a4fd866e
- DOI
- 10.20517/and.2024.15