Article

Mis-expression of the Alzheimer’s disease associated gene Ankyrin causes memory loss and shortened lifespan in <i>Drosophila</i>

2018-09-20

Abstract excerpt

<h4>ABSTRACT</h4> Alzheimer’s disease (AD) is the most common form of dementia and is characterized by the accumulation of extracellular amyloid beta (Aβ) plaques and intracellular neurofibrillary tangles of hyperphosphorylated Tau, including the 4R0N isoform. Recent epigenome-wide association studies (EWAS) of AD have identified a number of loci that are differentially methylated in AD cortex. Indeed, hypermethy...

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Literature Corpus work: a1b894e8-3537-5385-a3ad-1ed7951e3426
DOI: 10.1101/423129

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