Article

Transgenerational epigenetic inheritance mediated by the acetyltransferase MYS-2/MOF in the pathogenesis of Alzheimer’s disease

2023-04-27

Abstract excerpt

<title>Abstract</title> <bold>Background</bold> Although autosomal-dominant inheritance is believed to be an important cause of familial clustering AD (FAD), it covers only a small proportion of FAD incidence. Epigenetic memory has been suggested an alternative mechanism to explain transgenerational phenotypes in animals, and may contribute to intergenerational AD pathogenesis.<bold>Methods</bold> We employed...

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Literature Corpus work: afb41ad6-58af-52d7-8a4d-c9da3ec66a34
DOI: 10.21203/rs.3.rs-2850041/v1

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