Article

Identifying Factors Important for Conservation at Sites of Synonymous Variations

2024-01-02

Abstract excerpt

Synonymous mutations can have a deleterious effect leading to disease, even though they are not protein altering. Variations at genomic sites leading to synonymous variants are frequently highly conserved across species. Several prediction methods have been developed to assess the impact of synonymous mutations and are highly dependent on having validated sets of both deleterious and benign synonymous mutations. H...

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Literature Corpus work: a19e9746-bf91-5252-be76-7f7403784f92
DOI: 10.1101/2024.01.01.573819

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