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Article

Regions of extreme synonymous codon selection in mammalian genes.

Nucleic acids research - 1 Jan 2006

Schattner Peter, Diekhans Mark

Abstract excerpt

Recently there has been increasing evidence that purifying selection occurs among synonymous codons in mammalian genes. This selection appears to be a consequence of either cis-regulatory motifs, such as exonic splicing enhancers (ESEs), or mRNA secondary structures, being superimposed on the coding sequence of the gene. We have developed a program to identify regions likely to be enriched for such motifs by...

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PMID: 16556911
DOI: 10.1093/nar/gkl095
PMCID: PMC1410912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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