Article
Association between <i>CCR5</i>-Δ32 homozygosity and mortality in 37,650 participants from three U.S.-based cohorts
2019-10-03
Abstract excerpt
An analysis of 409,693 UK Biobank participants recently published in Nature Medicine identified a relative 21% increase in all-cause mortality among participants who were homozygous for the Δ32 deletion in the C-C motif chemokine receptor 5 gene ( CCR5 ). 1 This is a timely and potentially cautionary result in light of He Jiankui’s controversial germline editing of CCR5 to induce mutations that putatively mimic th...
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Identifiers and source
- Literature Corpus work
- a13be8a5-b85e-525a-b13e-6f7b3163cbba
- DOI
- 10.1101/19006619