Article
Effect of CCR5-Δ32 heterozygosity on HIV-1 susceptibility: a meta-analysis.
PloS one - 1 Jan 2012
Liu Sijie, Kong Chuijin, Wu Jie, Ying Hao, Zhu Huanzhang
Abstract excerpt
BACKGROUND: So far, many studies have investigated the distribution of CCR5 genotype between HIV-1 infected patients and uninfected people. However, no definite results have been put forward about whether heterozygosity for a 32-basepair deletion in CCR5 gene (CCR5-Δ32) can affect HIV-1 susceptibility. METHODS: We performed a meta-analysis of 18 studies including more than 12000 subjects for whom the CCR5-Δ32...
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