Article

Natural Variation in Age-Related Dopamine Neuron Degeneration is Glutathione-Dependent and Linked to Life Span

2024-02-14

Abstract excerpt

<h4>SUMMARY</h4> Aging is the biggest risk factor for Parkinson’s disease (PD), suggesting that age-related changes in the brain promote dopamine neuron vulnerability. It is unclear, however, whether aging alone is sufficient to cause significant dopamine neuron loss and if so, how this intersects with PD-related neurodegeneration. Here, through examining a large collection of naturally varying Drosophila strain...

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Literature Corpus work: a12aa770-96d2-550e-abb4-66d434d2ca80
DOI: 10.1101/2024.02.12.580013

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