Article
Behavioral screening defines three molecular Parkinsonism subgroups in <i>Drosophila</i>
2024-08-27
Abstract excerpt
Parkinsonism is defined by motor dysfunction, but the specific upstream molecular causes of these clinical symptoms can vary widely. We hypothesize that these causes converge onto a limited number of core cellular pathways. To investigate this, we created a new collection of 24 genetically very well-controlled animal models of familial forms of parkinsonism. Using unbiased behavioral screening and machine learning...
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Identifiers and source
- Literature Corpus work
- 1ecf7055-11c1-5cc7-913e-4f1772aec2d7
- DOI
- 10.1101/2024.08.27.609924