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The Scarred Circuitry of Fear: A Computational–Clinical Synthesis of PTSD Neurobiology

2026-01-12

Abstract excerpt

Post-traumatic stress disorder (PTSD) can be understood as a disorder of threat inference: after trauma, the brain assigns excessive probability and excessive cost to danger, while failing to consolidate safety when objective contingencies change. This article synthesizes convergent findings across fear-circuit neurobiology—amygdala reactivity, ventromedial prefrontal and anterior cingulate regulatory control, and...

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Literature Corpus work
a09dd501-8626-54e0-9a76-0b34941ed81d
DOI
10.32388/76fbo7
Open publication

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The Scarred Circuitry of Fear: A Computational–Clinical Synthesis of PTSD NeurobiologyDOI 10.32388/76fbo7
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