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A formal model of anxiety disorders based on the neural circuit dynamics of the fear and extinction circuits

2025-01-20

Abstract excerpt

The pathophysiology of anxiety disorders is the outcome of an imbalance of the fear-anxiety circuit and the extinction circuit. We present a formal model using nonlinear dynamics and network theory, which captures the dynamic interactions of the key nodes of the anxiety and extinction networks. This rudimentary model can be modified by newer data. These core nodes consist of the cells of the paraventricular nucleu...

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Literature Corpus work
17673ba6-2678-5e99-ad91-e8cbdc7b64da
DOI
10.1101/2025.01.20.633839
Open publication

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A formal model of anxiety disorders based on the neural circuit dynamics of the fear and extinction circuitsDOI 10.1101/2025.01.20.633839
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