Article
Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology - 1 Nov 2015
Norrholm Seth Davin, Glover Ebony M, Stevens Jennifer S, Fani Negar, Galatzer-Levy Isaac R, Bradley Bekh, Ressler Kerry J, Jovanovic Tanja
Abstract excerpt
Psychophysiological measures of fear expression provide observable intermediate phenotypes of fear-related symptoms. Research Domain Criteria (RDoC) advocate using neurobiological intermediate phenotypes that provide dimensional correlates of psychopathology. Negative Valence Systems in the RDoC matrix include the construct of acute threat, which can be measured on a physiological level using potentiation of the...
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