Article

Post-trauma behavioral phenotype predicts vulnerability to fear relapse after extinction

2021-09-25

Abstract excerpt

Current treatments for trauma-related disorders remain ineffective for many patients. Here, we modeled interindividual differences in post-therapy fear relapse with a novel ethologically relevant trauma recovery paradigm. After traumatic fear conditioning, male rats underwent fear extinction while foraging in a large enriched arena, permitting the expression of a wide spectrum of behaviors, assessed by an automate...

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Literature Corpus work: 954606c7-41e0-52ab-8bf1-8e63986ab504
DOI: 10.1101/2021.09.25.461769

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