Article

Endocannabinoid and neuroplasticity-related changes as susceptibility factors in a rat model of posttraumatic stress disorder

2024-03-07

Abstract excerpt

Traumatic experiences result in the development of posttraumatic stress disorder (PTSD) in 10-25% of exposed individuals. While human clinical studies suggest that susceptibility is potentially linked to endocannabinoid (eCB) signaling, neurobiological PTSD susceptibility factors are poorly understood. Employing a rat model of PTSD, we characterized distinct resilient and susceptible subpopulations based on genera...

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Literature Corpus work: 8fb7204c-e74c-50ea-b598-d3d465b8dac6
DOI: 10.1101/2024.03.06.583339

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