Article

H3k27ac-HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility

2020-10-25

Abstract excerpt

Genome-wide association studies (GWAS) have identified more than 140 prostate cancer (PrCa) risk regions which provide potential insights into causal mechanisms. Multiple lines of evidence show that a significant proportion of PrCa risk can be explained by germline causal variants that dysregulate nearby target genes in prostate-relevant tissues thus altering disease risk. The traditional approach to explore this...

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Literature Corpus work: a09c8cba-839e-5072-9079-113deb7668d1
DOI: 10.1101/2020.10.23.352351

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